くすりのしおり

Internal
Published: 4/2021

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ATORVASTATIN Tablets 5 mg "Me"
 Active ingredient:
Atorvastatin calcium hydrate
 Dosage form:
very light pink tablet, diameter: 5.6 mm, thickness: 2.6 mm
 Print on wrapping:
(Face)アトルバスタチン 5 mg「Me」, アトルバスタチン, 5 mg, 5, meiji
(Back)ATORVASTATIN 5 mg「Me」, アトルバスタチン「Me」, 5 mg, 高コレステロール血症治療剤

Effects of this medicine

This medicine lowers cholesterol in the blood by inhibiting cholesterol synthesis (HMG-CoA reductase) in the liver.
It is usually used to treat hypercholesterolemia or familial hypercholesterolemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: liver disorder or renal disorder.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For hypercholesterolemia: In general, for adults, take 2 tablets (10 mg of atorvastatin) at a time, once a day. The dosage may be adjusted according to the age or symptoms. For severe patients, the dosage may be increased up to 4 tablets (20 mg) a day.
    For familial hypercholesterolemia: In general, for adults, take 2 tablets (10 mg of atorvastatin) at a time, once a day. The dosage may be adjusted according to the age or symptoms. For severe patients, the dosage may be increased up to 8 tablets (40 mg) a day.
    In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Make sure you have a proper diet and exercise therapy.
  • Do not take grapefruit juice with this medicine, since it may intensify the therapeutic effects of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastric distress, itch, numbness of limbs, insomnia, diarrhea, heartburn, constipation, headache and general malaise. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • muscle pain, lassitude, reddish brown urine  [rhabdomyolysis, myopathy, immune-mediated necrotizing myopathy]
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva [fulminant hepatitis, hepatitis, liver dysfunction, jaundice]
  • sore throat, headache, limb subcutaneous bleeding [agranulocytosis, pancytopenia, thrombocytopenia]
  • erythema, erosion, fever [toxic epidermal necrolysis, muco-cutaneo-ocular syndrome, erythema multiforme]
  • dry mouth, increase of urine output, fatiguability [hyperglycemia, diabetes mellitus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.