Effects of this medicine
This medicine suppresses function of TNF (tumor necrosis factor)-α, which is one of the possible primary causative substances in juvenile idiopathic arthritis. TNF is one of the cytokines existing inside of the body even in a healthy state, and involved in activities of immunity and development of inflammation or pain.
It is usually used to treat active, polyarticular-course juvenile idiopathic arthritis with inadequate response to conventional therapies.
Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- In general, for patients weighing 15 kg to less than 30 kg, inject 1 syringe (20 mg of the active ingredient) subcutaneously at a time, once every two weeks. For patients weighing 30 kg or over, inject 2 syringes (40 mg) subcutaneously at a time, once every two weeks. In any case, strictly follow the instructions.
- Inject this medicine to the thighs, abdomen or arms. Injection site should be rotated and changed every time you inject this medicine. Do not inject this medicine to sensitive area of skin, wound site, rash or psoriasis. Do not massage the subcutaneous injection site.
- Inject this medicine to the area at least 3 cm apart from the previously injected site.
- Please use the whole amount at one time.
- If you miss an injection, contact your doctor. You should never inject two doses at one time.
- If you accidentally inject more than your prescribed dose, consult with your doctor or pharmacist.
- Do not stop injecting this medicine unless your doctor instructs you to do so.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include headache, upper respiratory tract infection (nasopharyngitis, etc.), cough, diarrhea, rash, itch, eczema, tinea infection, fever and injection site reaction (erythema, bleeding, swelling, induration, etc.). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- rapid high fever with chills and trembling, cough/phlegm [serious infections such as sepsis and pneumonia]
- prolonged slight fever/cough (2 weeks or longer), general malaise, weight loss [tuberculosis]
- joint pain, muscle pain, skin eruption [lupus-like syndrome]
- reduced visual acuity/double vision, numbness/pain/motor paralysis [demyelinating disease]
- dyspnea, hives, swelling around the eyes or lips [serious allergic reaction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.