くすりのしおり

Internal
Published: 6/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
GALANTAMINE OD Tablets 4 mg "TOWA"
 Active ingredient:
Galantamine hydrobromide
 Dosage form:
faint yellow tablet, diameter: 6.0 mm, thickness: 3.0 mm
 Print on wrapping:
(Face)ガランタミン OD 4 mg 「トーワ」, ガランタミン OD, 4 mg
(Back)ガランタミン OD 4 mg, Galantamine OD 4, TOWA, 東和薬品, ガランタミン 「トーワ」, OD, 4 mg

Effects of this medicine

This medicine inhibits an enzyme which hydrolyzes the neurotransmitter acetylcholine in brain, increase the amount of acetylcholine in brain, promotes the transmission of nerve information, and slows progression of the symptoms of dementia such as memory loss.
It is usually used to slow progression of the symptoms of dementia associated with mild to moderate Alzheimer-type dementia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.If you have: heart diseases such as sick sinus syndrome, sinoatrial block and atrioventricular block, gastrointestinal obstruction, lower urinary tract obstruction, Parkinson's disease, Parkinson syndrome, liver disorder or renal disorder.If you have: condition just after an operation on the digestive tract or on the urinary bladder.If you have a history of gastric ulcer, duodenal ulcer, bronchial asthma or obstructive lung disease.If you have or have had: convulsive disorders such as epilepsy.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with giving 1 tablet (4 mg of galantamine) at a time, twice a day, and 4 weeks later, the dosage should be increased to 2 tablets (8 mg) at a time. The dosage may be increased to 3 tablets (12 mg) at a time, twice a day, according to symptoms, however, in the case of dosage increase, the increase should be made only after this medicine has been administered for 4 weeks or longer at the preceding dose level. Strictly follow the instructions.
  • This medicine should be taken after a meal wherever possible in order to lessen adverse reactions.
  • This medicine can be given with saliva only. Crush the tablet lightly with the tongue and have it swallow with saliva.
  • If you miss giving a dose, give the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never give two doses at one time.
  • If you accidentally give more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop giving this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • In patients with Alzheimer's disease, the ability to operate machinery such as driving a car may diminish. Since this medicine may cause dizziness or drowsiness, be aware of letting the patient engage in the operation of dangerous machinery such as driving a car.
  • As weight loss may occur, be attentive to your body weight changes.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, loss of appetite, diarrhea, decreased appetite and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • faint, shortness of breath, dizziness [syncope, bradycardia, heart block, QT prolongation]
  • rash with pus-filled blister [acute generalized exanthematous pustulosis]
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva [hepatitis]
  • muscle pain of limbs, lassitude, reddish brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.