Effects of this medicine
This medicine promotes reabsorption of water in renal tubule and suppresses abnormal excessive urination. It acts directly on intestinal smooth muscle to cause contraction. It contracts small arteries in abdominal organs, reduces portal blood flow, and temporary decreases portal blood pressure to stop esophageal bleeding due to portal hypertension.
It is usually used for differential diagnosis for diabetes insipidus, elimination of intestinal gas as pretreatment for gallbladder/renal pelvic scan, and urgent treatment for bleeding from esophageal varices.
Before using this medicine, be sure to tell your doctor and pharmacist
- If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have coronary arteriosclerosis or other arteriosclerotic disease, cardiac failure, asthma, hypertensive disorders of pregnancy, migraine, epilepsy, chronic nephritis, cardiovascular disease associated with hypertension or ischemic cardiac disease due to causes other than arteriosclerosis.
- If you are pregnant or breastfeeding.
- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- Pituitary diabetes insipidus: In general, this medicine is injected subcutaneously or intramuscularly, 2 to 3 times a day.
- Differential diagnosis for pituitary or renal diabetes insipidus: In general, this medicine is injected subcutaneously, intramuscularly or intravenously.
- Elimination of intestinal gas: In general, this medicine is injected subcutaneously or intramuscularly.
- Urgent treatment for bleeding from esophageal varices: In general, this medicine is continuously injected intravenously.
- Period of treatment will be deterrmined based on the efficacy of your response.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include headache, nausea/vomiting, hypouresis, rash, hives and flush. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- chills, palpitation, cold sweat, pale face [shock]
- muscular pain, numbness, lassitude, reddish brown urine [rhabdomyolysis]
- breathing difficulty, shortness of breath, general edema, dry cough, chest pain [cardiac failure, cardiac arrest]
- impaired mind, decreased concentration, unable to recognize time/place/name, deep sleep [mental confusion, coma]
- general malaise, decreased attention, headache, nausea, vomiting, convulsion [water intoxication]
- headache, nausea, vomiting, temporal decreased consciousness, paralysis of limbs on one side, difficulty speaking, leg pain when walking, weakness of lower limbs, tingling/itching skin [CNS disorder]
- extremely decreased urine output [anuria]
- palpitation/shortness of breath [ventricular tachycardia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.