くすりのしおり

Internal
Revised: 12/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Equa Tablets 50mg
 Active ingredient:
Vildagliptin
 Dosage form:
white to pale yellowish white tablet with a split line, diameter: 8.0 mm, thickness: 3.6 mm
 Print on wrapping:
(face) エクア 50 mg, 糖尿病用薬
(back) Equa 50 mg, エクア, 50 mg, NVR, FB, 糖尿病用薬

Effects of this medicine

This medicine inhibits the enzyme which degrades incretin, a hormone adjusting blood glucose level. It enhances insulin secretion depending on blood glucose level, and consequently improves blood glucose control.
It is usually used to treat type 2 diabetes mellitus.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: diabetic ketoacidosis, diabetic coma, type 1 diabetes mellitus, hepatic dysfunction, infection or external injury.
    If you are in perioperative period.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (50 mg of the active ingredient) at a time, twice a day, in the morning and in the evening. The dose can be 1 tablet (50 mg) at a time, once a day in the morning according to your symptoms. Strictly follow the instructions. For patients with moderate or severe renal dysfunction or end stage renal disease on dialysis, the dose can be 1 tablet (50 mg) at a time, once a day in the morning. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Strictly follow diet and exercise therapy instructed by your doctor.
  • The medicine may cause hypoglycemia. Pay attention when you work at heights, drive a car or operate dangerous machinery.
  • If you noticed any symptoms of hypoglycemia, take sufficient amount of sugar (sugar, glucose, soft drink, etc.). If you are taking the medicine concomitantly with an alfa-glucosidase inhibitor (medicines which delay absorption of sugar), ingest glucose in case of any hypoglycemic symptoms.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include constipation, hungry and asthenia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, yellow discoloration of skin and/or conjunctiva, loss of appetite [hepatitis, liver disorder]
  • swelling of eyelids/lips/tongue, difficulty breathing, hives [angioedema]
  • a sense of hunger, weakness, cold sweat [hypoglycemia]
  • muscle pain, weakness, reddish brown urine [rhabdomyolysis]
  • persistent severe abdominal pain, back pain, vomiting [acute pancreatitis]
  • abdominal bloating, abdominal pain, vomiting [intestinal obstruction]
  • dry cough, breathing difficulty, fever [interstitial pneumonia]
  • intensely itchy blisters [pemphigoid]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.