くすりのしおり

Injection
Revised: 7/2021

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Xolair for s.c. injection 150mg syringe
 Active ingredient:
Omalizumab (genetical recombination)
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine suppresses IgE in the body, which is responsible for bronchial asthma, and relieves airway inflammation to prevent asthma attack. It is not intended to control an asthmatic attack which has already developed. It also relieves symptoms of seasonal allergic rhinitis or chronic idiopathic urticaria.
It is usually used to treat refractory bronchial asthma, whose symptoms are not able to be controlled with conventional therapy, to treat severe or most severe seasonal allergic rhinitis for which the effect of conventional therapy is insufficient, and to treat refractory chronic spontaneous/idiopathic urticaria (CSU/CIU) for which the effect of conventional therapy is insufficient.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itches, rashes, etc.) to any medicines.
  • If you have allergy to latex.
  • If you are pregnant or are breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Bronchial asthma, seasonal allergic rhinitis : In general, inject subcutaneously once every 2 or 4 weeks. Dosing frequency is determined according to your blood IgE level and body weight prior to starting this medicine.
  • Chronic spontaneous/idiopathic urticaria: In general, subcutaneously every 4 weeks.
  • Ask your doctor about the specific duration of use.

Precautions while taking this medicine

  • The medicine may cause dizziness, fatigue, syncope or drowsiness. Pay close attention when driving a car or operating dangerous machinery.
  • The use of this medicine may change/affect the symptoms of other allergic disorders. In such cases, please consult with your doctor responsible for them.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include injection site reaction (erythema, swelling, itching, etc), headache and hives. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • breathing difficulty, decreased consciousness, swelling of tongue/lips/throat [shock, anaphylaxis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.