くすりのしおり

Injection
Published: 8/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
SIVEXTRO for iv infusion 200mg
 Active ingredient:
Tedizolid phosphate
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine is an oxazolidinone antibiotic that is converted to active substance tedizolid in the body, and shows antibacterial effect by inhibiting protein synthesis of bacteria.
It is usually used for the treatment of deep skin infections, chronic pyoderma, infection secondary to wound, burn, surgical wound or infection secondary to erosion or ulcer, caused by methicillin-resistant Staphylococcus aureus (MRSA).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, inject by intravenous infusion over 1 hour once a day.
  • Ask the doctor about the treatment span.
  • Lie/sit quietly from the beginning to the end of drip infusion.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include injection site reaction (e.g., erythema, pain, phlebitis), abnormal hepatic function, anemia, diarrhea, discomfort in limbs, itchy eruption, vascular pain and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • abdominal pain, frequent diarrhea [pseudomembranous colitis]
  • anemia symptoms (e.g., dizziness on standing up, headache), fever, bleeding tendency (e.g., subcutaneous bleeding, nose bleeding) [marrow depression such as reversible anemia/leucopenia/pancytopenia/thrombocytopenia]
  • hyperventilation, decreased consciousness, palpitation [metabolic acidosis]
  • reduced visual acuity, defective color vision, foggy vision/defect in the visual field [optic neuropathy]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.