Search results detail| Kusurino-Shiori(Drug information Sheet)

NIPRO CORPORATION

Internal
Revised: 7/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.

Brand name :

ARIPIPRAZOLE POWDER 1% "NIPRO"

　Active ingredient:

Aripiprazole

　Dosage form:

white powder

　Print on wrapping:

Effects of this medicine

This medicine acts on receptors of the brain neurotransmitter dopamine, etc. and suppresses symptoms such as hallucinations/delusions, thereby improving symptoms such as lowering of motivation and stabilizing unstable mental states.
It is usually used to treat schizophrenia and improve manic episodes associated with bipolar disorder.

Before using this medicine, be sure to tell your doctor and pharmacist

If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have diabetes mellitus or a personal or family history of diabetes mellitus.
If you have: liver disorder, cardiovascular disease, hypotension, convulsive disorders such as epilepsy or a history of convulsive disorders.
If you have attempted or are considering suicide.

If you are pregnant or breastfeeding.

If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))

For schizophrenia: In general, for adults, start with taking 0.6 to 1.2 g (6 to 12 mg of the active ingredient) daily at one time or in two divided doses, then take 0.6 to 2.4 g (6 to 24 mg) daily at one time or in two divided doses as a maintenance dose. The dosage may be adjusted according to age and symptoms. However, the daily dose should not exceed 3.0 g (30 mg).
For improvement of manic episodes associated with bipolar disorder: In general, for adults, take 1.2 to 2.4 g (12 to 24 mg of the active ingredient) at one time, once daily. The starting dose is determined as 2.4 g (24 mg), and the dosage may be adjusted according to age and symptoms. However, the daily dose should not exceed 3.0 g (30 mg).
In any case, strictly follow the instructions.

If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.

If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

This medicine may cause sleepiness and decrease attention/concentration/reflex movement performance, etc. Avoid working at heights or operating dangerous machinery, such as driving a car.
Avoid drinking alcohol while taking this medicine because it may intensify medicinal or medical effects.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include insomnia, nervousness, anxiety, somnolence, dizziness, headache, akathisia (inability to sit still), tremor, salivation (excess saliva), akinesia (small movements of facial expression), dystonia (abnormal muscle tone), articulatory disorder, muscle rigidity, constipation, nausea, abdominal pain, diarrhea, loss of appetite, bulimia, dry mouth, increased body weight, decreased body weight, malaise, lassitude, fever and increased sweat. If any of these symptoms occur, consult with your doctor or pharmacist.

The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.

acute onset of fever, rapid pulse, muscle stiffness [neuroleptic malignant syndrome]
continuous chewing-like movements of the mouth with tongue movements or protrusion and retraction [tardive dyskinesia]
loss of appetite, nausea, severe constipation [paralytic ileus]
rash, itch, respiratory distress [anaphylaxis]
muscle pain, lassitude, reddish-brown urine [rhabdomyolysis]

The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them. Seek advice of your pharmacy or medical institution about proper disposal of the unused medicines.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.