くすりのしおり

Internal
Published: 12/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Tamoxifen Tab.20mg "MYL"
 Active ingredient:
Tamoxifen citrate
 Dosage form:
white tablet, diameter: 8.1 mm, thickness: 4.2 mm
 Print on wrapping:
(face) T20, 20, (back) Tamoxifen 20mg「MYL」, タモキシフェン 20mg「MYL」, Mylan

Effects of this medicine

This medicine binds to estrogen receptor of breast cancer tissue in a competitive manner. It exerts an antiestrogen effect to suppress growth of breast cancer cell.
It is usually used to treat breast cancer.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: decreased white blood cell or decreased platelets.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (20 mg of tamoxifen) at a time, once a day. The dosage may be adjusted according to the symptoms. The maximum daily dose is up to 2 tablets (40 mg). Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Use nonhormonal forms of contraception while taking this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include amenorrhoea, menstruation abnormal, genital bleeding, nausea/vomit, loss of appetite and hot flush/flush. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • sore throat, fever, anaemia [agranulocytosis, decreased white blood cell, decreased neutrophils, anaemia, decreased platelets]
  • reduced visual acuity, focus disorder, foggy vision [abnormal visual acuity, vision disorder]
  • localized pain, swelling, fever [thromboembolism, venous inflammation]
  • general malaise, loss of appetite, yellowing of the skin and the white of eyes [fulminant hepatitis, hepatitis, biliary engorgement, liver failure]
  • atypical genital bleeding [uterine myoma, endometrial polyp, endometrial hyperplasia, endometriosis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.