くすりのしおり

Internal
Published: 6/2015

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Letrozole Tablets 2.5mg "Nichiiko"
 Active ingredient:
Letrozole
 Dosage form:
reddish yellow tablet, diameter: 6.1 mm, thickness: 3.3 mm
 Print on wrapping:
レトロゾール錠2.5mg「日医工」,レトロゾール,n337,2.5mg,日医工,Letrozole Tab. 2.5mg,レトロゾール2.5mg「日医工」,1日1回1錠

Effects of this medicine

This medicine inhibits aromatase activity to inhibit the conversion of androgen into estrogen, and suppresses the the growth of breast cancer.
It is usually used to treat postmenopausal breast cancer.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (2.5 mg of the active ingredient) at a time, once a day. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause fatigue, dizziness or sleepiness. Be aware of operating in potentially hazardous activities such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include hot flash, headache, joint pain, nausea, rash, itch and dizziness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, localized pain, tenderness [thrombosis, embolism]
  • respiratory distress, chest pain, sensation of pressure [heart failure, angina pectoris]
  • general malaise, loss of appetite, yellowing of the skin and the whites of the eyes [liver dysfunction, jaundice]
  • high fever, ocular injection, erythema [toxic epidermal necrolysis, erythema multiforme]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist or medical facility how to discard unneeded medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.