くすりのしおり

Injection
Revised: 11/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Oxaliplatin I.V. Drip Infusion 100mg "Nichiiko"
 Active ingredient:
Oxaliplatin
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine inhibits DNA synthesis of cancer cells to suppress proliferation of cancer cell.
It is usually used to treat incurable/unresectable and advanced/recurrent colon/rectal cancer, incurable/unresectable pancreatic cancer, gastric cancer and small intestinal cancer, and for the adjuvant chemotherapy of colon cancer.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have paresthesia with functional impairment or dysesthesia.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, inject by intravenous infusion for 2 hours, once a day.
  • The interval of injection may be decided according to concomitant medicines and symptoms of the patient. Ask the doctor for the detailed schedule.

Precautions while taking this medicine

  • Paresthesia or dysesthesia (peripheral nerve symptoms) of limbs or around lip occur easily or become worse by low temperature or touching something cold. During treatment period, avoid intake of cold drinks or ice, and do not expose your skin when the temperature is low.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, diarrhea, vomiting, loss of appetite, stomatitis, fatigue and malaise. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • numbness of limbs, hard to button, swallowing difficulty [peripheral nerve symptoms]
  • rash, itch, bronchospasm [shock, anaphylaxis]
  • fever, cough, respiratory distress [interstitial pneumonitis, pulmonary fibrosis]
  • anemia symptoms, fever, bleeding tendency [myelosuppression]
  • fever, anemia symptoms, purpura [hemolytic-uremic syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.