くすりのしおり

Injection
Published: 12/2012

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Cisplatin Injection 50mg "Nichiiko"
 Active ingredient:
Cisplatin
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine inhibits DNA synthesis of cancer cells to suppress proliferation of cancer cells.
It is usually used to treat testicular tumor, bladder cancer, renal pelvis/ureteral tumor, prostate cancer, ovary cancer, head and neck cancer, non-small-cell lung cancer, esophageal cancer, cervical cancer, neuroblastoma, gastric cancer, small cell lung cancer, osteosarcoma, germ cell tumor (testicular tumor, ovarian tumor, extragonadal tumor), malignant pleural mesothelioma and biliary tract cancer, and for use of the combination therapy with other antineoplastic drug in malignant bone tumor, endometrial cancer, recurrent/intractable malignant lymphoma and childhood malignant solid tumor.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have renal disorder.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, inject by intravenous infusion.
  • For protection of kidney, water is supplied by intravenous infusion before and after injection of this medicine.
    For prevention of nausea, antiemetic agent may be administered in advance.
  • The interval of injection may be decided according to concomitant drugs and symptoms of the patient. Ask the doctor for the detailed schedule.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea/vomiting, loss of appetite, rash, hot flash, hair loss and general malaise. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • bloody urine, decreased urine output, swelling of limbs and face [acute renal failure]
  • anemia symptoms, fever, bleeding tendency [myelosuppression such as pancytopenia]
  • pale face, respiratory distress, hives [shock, anaphylactoid symptoms]
  • decreased hearing in high tone range, deafness, ringing in the ear [decreased hearing/deafness, tinnitus]
  • reduced visual acuity, complete loss of vision due to disorder in cerebral visual cortex [papilledema, retrobulbar neuritis, cortical blindness]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.