Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- For slowing progression of symptoms of dementia associated with Alzheimer's disease: In general, for adults, give 3 mg as the active ingredient at a time once a day for the first one to two weeks. Subsequently, the dose will be increased to 5 mg at a time once a day. Additionally, if the disease has progressed, after giving 5 mg at a time once a day for more than 4 weeks, the daily dose will be increased to 10 mg at a time once a day. The dosage should be decreased according to the symptoms.
For slowing progression of symptoms of dementia associated with Lewy body dementia: In general, for adults, give 3 mg as the active ingredient at a time once a day for the first one to two weeks. Subsequently, the dose will be increased to 5 mg at a time once a day. Additionally, after giving 5 mg at a time once a day for more than 4 weeks, the daily dose will be increased to 10 mg at a time once a day. The dosage may be decreased to 5 mg at a time once a day according to the symptoms.
This preparation contains 5 mg of the active ingredient in a tablet. In any case, strictly follow the instructions.
- If the dosage is increased to 10 mg at a time once a day, pay attention to gastrointestinal adverse reactions.
- If you miss giving a dose, give a dose as soon as you notice it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never give two doses at one time.
- If you accidentally give more than your prescribed dose, consult with your doctor or pharmacist.
- Do not stop giving this medicine unless your doctor instructs you to do so.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include rash, itchiness, loss of appetite, nausea/vomiting, diarrhea, abdominal pain, agitation, restlessness, insomnia and wandering. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- loss of consciousness, chest pain, shortness of breath [QT prolongation, ventricular tachycardia, ventricular fibrillation, sick sinus syndrome, sinus pause, severe bradycardia, syncope, heart block, myocardial infarction, heart failure]
- heartburn, abdominal pain, black stool, bloody stool, fever [peptic ulcer, duodenal ulcer perforation, gastrointestinal hemorrhage]
- nausea/vomiting, loss of appetite, yellowing of the skin or whites of the eyes [hepatitis, hepatic dysfunction, jaundice]
- convulsion, severe headache, nausea/vomiting [cerebral seizure, cerebral hemorrhage, cerebrovascular disorder]
- slow movement, involuntary movement of the mouth/tongue/limbs, abnormal muscular contraction, shaking of the limbs [extrapyramidal disorder]
- high fever, muscle stiffness, semi-consciousness [malignant syndrome]
- muscle pain, lassitude, reddish brown urine [rhabdomyolysis]
- shortness of breath, breathing difficulty [respiratory distress]
- upper abdominal/lower back pain, nausea/vomiting [acute pancreatitis]
- general edema, decreased urine output [acute kidney injury]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.