くすりのしおり

Injection
Revised: 7/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
NESP INJECTION 30mcg PLASTIC SYRINGE[anemia with myelodysplastic syndromes]
 Active ingredient:
Darbepoetin Alfa(Genetical Recombination)
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine acts on cells that grow into red blood cells (RBCs) to increase the number of RBCs.
It is usually used in the treatment of anemia with myelodysplastic syndromes.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have a history of myocardial infarction, pulmonary infarction or cerebral infarction.
    If you have: hypertension.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, inject subcutaneously once per week. Ask your doctor about the dosing instructions.
  • You will be administered this medicine over a long time under the monitoring of efficacy.
  • If you use this medicine for the first time or after an interval, you may be administered lower dose subcutaneously and observed whether any abnormalities occur.

Precautions while taking this medicine

  • You need to take iron to get an adequate efficacy. If you are prescribed iron preparation, you should take it as instructed by your doctor.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include increased blood pressure, hepatic function disorder , headache, malaise and shunt thrombosis/occlusion. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • sudden weakness of limbs on one side, sudden vomiting, sudden difficulty speaking [cerebral infarction, cerebral hemorrhage]
  • general dullness, nausea, yellowing of the skin and the white of eyes [liver dysfunction, jaundice]
  • headache, early morning vomiting, temporary vision disorder [hypertensive encephalopathy]
  • hives, respiratory distress, edema of lip [shock, anaphylaxis]
  • general dullness, dizziness, palpitations [pure red-cell aplasia]
  • constrictive chest pain, breathing difficulty, cold sweat [myocardial infarction]
  • phlegm with blood, chest pain, breathing difficulty [pulmonary infarction]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.