くすりのしおり

Internal
Revised: 9/2021

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Amerge Tablets 2.5mg
 Active ingredient:
Naratriptan hydrochloride
 Dosage form:
green D-shaped tablet, major axis: 13.5 mm, minor axis: 7.5 mm, thickness: 3.9 mm
 Print on wrapping:
(face) アマージ2.5mg (back) Amerge2.5mg, アマージ2.5mg, 片頭痛治療剤, GX CE5, GSK, 乳幼児誤飲防止シート, 乳幼児の誤飲を防ぐため、錠剤が取出しにくくなってます

Effects of this medicine

This medicine contracts excessively dilated intracranial/extracranial blood vessels under migraine attack and puts them back to normal. It also reduces inflammation around the vessels by suppressing the release of the substance which causes inflammation.
It is usually used to treat migraine attacks and not used to prevent attacks.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: heart disease, peripheral vascular disorder, hypertension, liver disease, renal disease or organic brain disease such as epilepsy.
    If you have had: heart disease or cerebrovascular disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (2.5 mg of naratriptan) at a time when migraine attack occurs. If the effect is insufficient, take an additional dose at an interval of 4 or more hours. The maximum daily dose is 2 tablets (5 mg). If you have liver or renal disease, the maximum daily dose is 1 tablet (2.5 mg). Strictly follow the instructions.
  • If this medicine shows no effect for migraine, stop taking this medicine. It may not be a migraine, and a dangerous headache might be overlooked. Make sure you consult with your doctor.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.

Precautions while taking this medicine

  • This medicine may cause sleepiness. Do not operate dangerous machinery, such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, vomiting and pain in various parts of the body. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • dyspnea, cold sweat, dizziness on standing up [anaphylactic shock, anaphylaxis]
  • chest pain, chest tightness, cold sweat [ischemic heart disease-like symptoms]
  • exacerbation of headache, headache not improved [medication overuse headache]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist or medical institution on how to discard them.
  • This medicine is provided in complicated packaging to prevent infants/children from accidental swallowing. Open the package in consultation with your doctor or pharmacist.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.