くすりのしおり

Internal
Revised: 3/2021

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Zantac Tablets 75
 Active ingredient:
Ranitidine hydrochloride
 Dosage form:
white tablet, diameter: 7.1 mm, thickness: 3.2 mm
 Print on wrapping:
(face) ザンタック75mg, ザンタック75, 75 (back) Zantac75mg, GSK, ザンタック75mg, GX101

Effects of this medicine

This medicine suppresses the production of gastric acid by blocking histamine H2 receptors that are related to gastric acid secretion.
It is usually used to treat gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis and upper gastrointestinal bleeding, and to improve gastric mucosal lesions (erosion, bleeding, redness and edema) in patients with acute gastritis and acute exacerbation of chronic gastritis. It is also used for anesthetic premedication.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have renal or liver disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger-Ellison syndrome, reflux esophagitis and upper gastrointestinal bleeding: In general, for adults, take 2 tablets (150 mg of ranitidine) at a time, twice a day (after breakfast and before bedtime). However, you may also take 4 tablets (300 mg) at a time, once a day (before bedtime). The dosage may be adjusted according to the symptoms.
    For gastric mucosal lesions of acute gastritis and acute exacerbation of chronic gastritis: In general, for adults, take 1 tablet (75 mg of ranitidine) at a time, twice a day (after breakfast and before bedtime). However, you may also take 2 tablets (150 mg) at a time, once a day (before bedtime). The dosage may be adjusted according to the symptoms.
    Anesthetic premedication: In general, for adults, take 2 tablets (150 mg of ranitidine) at a time, twice (once before bedtime on the day before surgery and once 2 hours before anesthesia induction on the day of surgery).
    In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastrointestinal symptoms such as constipation and diarrhea, rash, itch, fever, angioedema and vasculitis. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, hives, facial pallor [shock, anaphylaxis]
  • general malaise, lassitude, subcutaneous/submucosal bleeding [blood disorder such as aplastic anemia and pancytopenia]
  • general malaise, vomit, yellowing of the skin [liver dysfunction, jaundice]
  • muscle pain in limbs, general malaise, reddish brown urine [rhabdomyolysis]
  • decreased consciousness, impaired mind, decreased judgment [consciousness disorder, convulsion, myoclonus]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.