くすりのしおり

Internal
Revised: 9/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Hepsera Tablets 10
 Active ingredient:
Adefovir pivoxil
 Dosage form:
white tablet, diameter: 7.0 mm, thickness: 2.9 mm
 Print on wrapping:

Effects of this medicine

This medicine decreases the amount of virus by suppressing the growth of the hepatitis B virus and improves liver function.
It is usually used to treat chronic hepatitis B virus infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take one tablet (10 mg of the active ingredient) at a time, once a day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so. Discontinuation of this medicine without permission may lead to disease progression.

Precautions while taking this medicine

  • It is important that you receive medical examination on a regular basis because symptoms of chronic hepatitis B and hepatic cirrhosis B are extremely difficult to detect on your own.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash and nausea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • decreased urine output, edema, headache [renal failure]
  • shaky hands, deep breaths, muscle weakness [Fanconi syndrome]
  • foot pain while walking, deformation such as bowlegs [osteomalacia, fracture]
  • hyperpnea, consciousness disorder, tremoring limbs [lactic acidosis]
  • adiposis in hypodermal tissues or internal organs, liver enlargement (pressured feeling in the right hypochondrium) [severe liver enlargement due to adiposis (fatty liver)]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacy or medical institution on how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.