くすりのしおり

Internal
Revised: 10/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Tosufloxacin Tosilate Tablets 150mg "Nichiiko"
 Active ingredient:
Tosufloxacin tosilate hydrate
 Dosage form:
white tablet, diameter: 8.6 mm, thickness: 4.9 mm
 Print on wrapping:
トスフロキサシントシル酸塩錠150mg,トスフロキサシントシル酸塩,n721,150mg,Tosufloxacin tosilate Tab.150mg,抗菌剤,トスフロキサシン150mg「日医工」

Effects of this medicine

This medicine is new quinolone antibiotic agent. It inhibits the synthesis of bacterial DNA to show bactericidal antibacterial effects.
It is usually used to treat various infections such as skin/respiratory/urinary/gynecologic/ophthalmologic/otolaryngologic/dental infections.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 to 3 tablets (300 to 450 mg of the active ingredient) a day, in 2 to 3 divided doses. The dosage may be adjusted according to disease, symptoms, etc. of the patient. If symptoms are severe or the effect is insufficient, take 4 tablets (600 mg) a day.
    Osteomyelitis, arthritis: In general, for adults, take 1 tablet (150 mg of the active ingredient) at a time, 3 times a day. The dosage may be adjusted according to disease, symptoms, etc. of the patient. If symptoms are severe or the effect is insufficient, take 4 tablets (600 mg) a day.
    Typhoid/paratyphoid fever: In general, for adults, take 1 tablet (150 mg of the active ingredient) at a time, 4 times a day for 14 days.
    Strictly follow the instructions in any case.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, stomach/abdominal discomfort, nausea, stomach/abdominal pain and diarrhea/loose stool. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, edema, flare [shock, anaphylactoid symptoms]
  • high fever, blister, bloodshot eyes [toxic epidermal necrolysis, mucocutaneous-ocular syndrome]
  • sudden onset of muscular contraction, faint consciousness [convulsion, impaired consciousness]
  • decreased urine output, edema of limbs and face, fever [acute renal failure, interstitial nephritis]
  • general malaise, loss of appetite, yellowing of the skin and the whites of the eyes [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.