くすりのしおり

Internal
Revised: 7/2011

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Tamoxifen Tablets 20mg "Nichiiko"
 Active ingredient:
Tamoxifen citrate
 Dosage form:
white tablet, diameter 10.0mm, thickness 4.3mm
 Print on wrapping:
タモキシフェンクエン錠20mg「日医工」,20mg,n121,Tamoxifen Tab.20

Effects of this medicine

This medicine acts on estrogen receptor of breast cancer cell to suppress estrogen actions and growth of cancer cell.
It is usually used to treat breast cancer.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 20mg of tamoxifen a day, in 1 to 2 divided doses. The dosage may be adjusted according to symptoms of the patient. DO NOT exceed the daily maximum dosage, 40mg. This preparation contains 20mg of the active ingredient in a tablet. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Use a nonhormonal fertility control while taking this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include amenorrhea, menstrual abnormality, genital bleeding, nausea, vomiting, anorexia, hot flash and flushing. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • reduced visual acuity, blurred vision [vision abnormality/disturbance]
  • local pain/tenderness, erythema, edema [thromboembolism, phlebitis]
  • genital bleeding, menstrual abnormality (hypermenorrhea, lower abdominal/low back pain, etc.), menstrual irregularity [uterine fibroid, endometrial polyp, endometrial hyperplasia, endometriosis]
  • fever, dry cough, respiratory distress [interstitial pneumonia]
  • swelling around eyelid/lip, rash, shortness of breath  [anaphylactoid symptoms, angioedema]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.