くすりのしおり

Internal
Revised: 1/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Aspirin "Nichiiko" [for antipyresis/analgesia/antiinflammation]
 Active ingredient:
Aspirin
 Dosage form:
white powder
 Print on wrapping:

Effects of this medicine

This medicine acts on hypothalamic thermoregulatory center to bring down fever. It also inhibits synthesis of prostagrandines to reduce pain and inflammation.
It is usually used to treat disorders associated with various pains caused by rheumatoid arthritis, osteoarthritis, etc. , bring down fever and relieve pains in acute upper respiratory tract infection.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have peptic ulcer, blood abnormality, liver disorder, renal disorder, cardiac dysfunction or aspirin-induced asthma or a history of it.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Rheumatoid arthritis, osteoarthritis, etc. : In general, take 0.5 to 1.5 g of the active ingredient at a time, 1.0 to 4.5 g a day. The dosage may be adjusted according to diseases, age and symptoms of the patient. DO NOT exceed the maximum dosage, 1.5 g at a time, 4.5 g a day.
    Antipyresis and analgesia in acute upper respiratory tract infection : In general, take 0.5 to 1.5 g of the active ingredient at a time, as needed. The dosage may be adjusted according to age and symptoms of the patient. Do not exceed the daily maximum number of doses, 2 times, and the daily maximum dosage, 4.5 g, in principle.
    Strictly follow the instructions in any case.
  • Do not take on an empty stomach.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Refrain from drinking alcohol while taking the medicine as gastrointestinal bleeding may be induced and intensified.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastrointestinal disorder, hives, rash, edema, rhinitis-like symptoms, anemia, platelet hypofunction (prolonged bleeding time), dizziness, headache, excitation, hyperpnea, malaise and hypoglycemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, generalized flush, angioedema [shock, anaphylaxis]
  • headache, nausea/vomiting, blood vomiting/melena [intracranial/gastrointestinal bleeding]
  • fever, bloodshot eyes, facial and general redness [toxic epidermal necrolysis, mucocutaneous-ocular syndrome, exfoliative dermatitis]
  • bruise, nasal bleeding, high fever [aplastic anemia, thrombocytopenia, leukopenia]
  • breathing difficulty, wheezing [asthma attack]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.