くすりのしおり

Internal
Revised: 1/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Aspirin "Nichiiko" [for Kawasaki disease]
 Active ingredient:
Aspirin
 Dosage form:
white powder
 Print on wrapping:

Effects of this medicine

This medicine shows antiinflammatory effect by inhibiting synthesis of prostagrandines. It also shows platelet aggregation inhibition by selectively inhibiting synthesis of prostagrandines in platelet to prevent blood clotting and vessel construction.
It is usually used to treat Kawasaki disease and its cardiovascular aftereffect.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have peptic ulcer, bleeding tendency, aspirin-induced asthma or a history of it.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Feverish period in acute phase : In general, take 30 to 50 mg of the active ingredient per kg of body weight (mg/kg) in 3 divided doses a day.
    Recovery phase to chronic phase after fever : In general, take 3 to 5mg/kg of the active ingredient at a time, once a day.
    The dosage may be adjusted according to symptoms of the patient in any case. Strictly follow the instructions.
  • Do not take on an empty stomach.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Refrain from drinking alcohol while taking the medicine as gastrointestinal bleeding may be induced and intensified.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include gastrointestinal disorder, hives, rash, edema, rhinitis-like symptoms, anemia, platelet hypofunction (prolonged bleeding time) , dizziness, headache, excitation, hyperpnea, malaise and hypoglycemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, generalized flush, angioedema [shock, anaphylaxis]
  • headache, nausea/vomiting, blood vomiting/melena [intracranial/gastrointestinal bleeding]
  • fever, bloodshot eyes, facial and general redness [toxic epidermal necrolysis, mucocutaneous-ocular syndrome, exfoliative dermatitis]
  • bruise, nasal bleeding, high fever [aplastic anemia, thrombocytopenia, leukopenia]
  • breathing difficulty, wheezing [asthma attack]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.