くすりのしおり

Internal
Revised: 3/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Benzbromarone Tablets 25mg "Nichiiko"
 Active ingredient:
Benzbromarone
 Dosage form:
white to faint yellow tablet with split line, diameter: 6.5 mm, thickness; 2.15 mm
 Print on wrapping:
ベンズブロマロン錠25mg「日医工」,n358,25mg,Benzbromarone Tab.25mg,ベンズブロマロン25mg「日医工」

Effects of this medicine

This medicine increases excretion of uric acid into the urine by inhibiting reabsorption of uric acid in renal tubules in order to improve hyperuricemia.
It is usually used to improve hyperuricemia accompanied with gout and hypertension with hyperuricemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have liver/renal disorder and nephrolithiasis.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Gout: In general, for adults, take 1 to 2 tablets (25 mg to 50 mg of the active ingredient) at a time once a day, 2 tablets (50 mg) at a time once to 3 times a day as maintenance dose thereafter.
    Hypertension with hyperuricemia: In general for adults, take 2 tablets (50 mg of the active ingredient) at a time once to 3 times a day .
    The dosage may be adjusted according to disease, age and symptoms of the patient in any case. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Periodical liver function test is carried out for the first six months from the start of taking this medicine. The liver function test may be performed on a regular basis on and after the sixth month. Do not miss appointments with your doctor.
  • Uric acid stone and symptoms (hematuria, renal colic) may occur when your urine has acidity. To prevent these symptoms, take plenty of water to increase urinary volume and alkalize urine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include itch, rash, hives, facial redness, erythema, photosensitivity and jaundice. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, loss of appetite, yellowing of the skin and the whites of the eyes [serious liver disorder]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist or medical facility how to discard unneeded medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.