Effects of this medicine
This medicine increases gamma-aminobutyric acid (GABA, an inhibitory neurotransmitter) or dopamine consistency in the brain, and promotes metabolism of serotonin to activate inhibitory systems in the brain and to show antiepileptic action. It is also considered that promoting effect of GABA neurotransmission contributes to antimanic effect.
It is usually used in the treatment of various types of epilepsy, personality and behavior disorders resulting from epilepsy (moroseness, irascibility, etc.), mania and manic phase of manic-depressive psychosis.
Before using this medicine, be sure to tell your doctor and pharmacist
- If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you are a patient with liver disorder, encephalopathy or coma of unknown cause, or urea cycle disorder.
If you have a family history of infant death of unknown cause.
- If you are pregnant, possible pregnant or breastfeeding.
- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- In general, take 4 to 12 tablets (400 to 1,200 mg of the active ingredient) daily, in two or three divided doses. The dosage may be adjusted according to the disease, age or symptoms. Strictly follow the instructions.
- If you missed a dose, take a dose as soon as possible or it may result in developing an epileptic seizure (symptom). After taking the medicine, wait about 4 hours to take the next dose. You should never take two doses at one time.
- If you accidently took too much of the medicine (more than instructed), check with your doctor/pharmacist.
- Do not stop taking this medicine unless your doctor instructs you to do so.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include somnolence, ataxia (cannot coordinate leg and arm movements), headache, sleeplessness, restlessness, abnormal vision, nausea / vomiting, loss of appetite, stomach discomfort, constipation, rash, enuresis / frequent urination, malaise and bleeding from nose. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- acute decreased consciousness, general dullness / loss of appetite, yellowing of the skin and the white of eyes [serious liver disorder such as fulminant hepatitis, jaundice, fatty liver]
- loss of memory, irrational behavior, struggle [consciousness disturbance associated with hyperammonemia]
- general dullness, dizziness, bruise [hemolytic anemia, pure red-cell aplasia, pancytopenia, serious thrombocytopenia, granulocytopenia]
- intense abdominal pain, fever, nausea [acute pancreatitis]
- fever, bloodshot eyes, sores around the eyes and the lips, widespread skin redness and multiple breakable blisters [toxic epidermal necrolysis, oculomucocutaneous syndrome]
- dry cough, shortness of breath, fever [interstitial pneumonia, eosinophilic pneumonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.