Effects of this medicine
This medicine suppresses calcium ion influx into cells which causes contraction of the heart and vessels, to dilate the coronary vessel and to decrease total peripheral vascular resistance. It consequently shows antihypertensive effects and antianginal effects.
It is usually used in the treatment of essential hypertension, renal hypertension and angina pectoris.
Before using this medicine, be sure to tell your doctor and pharmacist
- If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
If you are a patient with cardiogenic shock, aortic valve stenosis, mitral valve stenosis, pulmonary hypertension, excessive hypotension, renal dysfunction, hepatic dysfunction or congestive heart failure.
If you are on hemodialysis.
- If you are pregnant or breastfeeding.
- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- General dosage regimen:
For essential hypertension and renal hypertension, for adults, take 1 to 2 tablets (10-20 mg of the active ingredient) at a time, twice daily.
For angina pectoris, for adults, take 2 tablets (20 mg of the active ingredient) at a time, twice daily.
The dosage may be adjusted according to the symptoms in any case. Strictly follow the instructions of your doctor/pharmacist.
- Swallow the medicine without splitting or chewing since it is a sustained-release tablet. If you chew and swallow it, the blood concentration will increase and may cause side effects such as headache or facial flush.
- Take a dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. DO NOT take double doses to make up for the missed dose.
- If you took too much of the medicine (more than ordered), check with your doctor/pharmacist.
- Do not stop taking the medicine without the instructions of your doctor.
Possible adverse reactions to this medicine
Common side effects are reported as below. If any of them occurs, check with your doctor/pharmacist: facial flush, dizziness, headache, jaundice, chest pain, upper abdominal pain, rash, itch, photosensitivity, purpura, gingival hyperplasia, anemia, breathing difficulty, gynecomastia, etc.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- general redness, skin exfoliation, fever, general malaise [erythroderma (exfoliative dermatitis)]
- headache, fever, throat pain, muscle pain, nasal bleeding, subcutaneous bleeding [agranulocytosis, thrombocytopenia]
- facial pallor, cold sweat, orthostatic dizziness, decreased conscious [shock]
- decreased conscious, disturbed thinking, decreased judgement [conscious disorder]
- general malaise, yellowing in the skin and the white of the eye, loss of appetite [hepatic dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.