くすりのしおり

Injection
Revised: 12/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
SYNVISC DISPO INTRA-ARTICULAR INJECTION 2mL
 Active ingredient:
Sodium hyaluronate crosslinked polymer
Sodium hyaluronate crosslinked polymer crosslinked with vinylsulfone
 Dosage form:
Injection
 Print on wrapping:

Effects of this medicine

This medicine is injected into the joint. It replaces joint fluid which acts as a lubricant or cushion.
It is usually used to relieve pain associated with osteoarthritis of the knee.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have previously experienced chills, nausea, chest distress, acute respiratory distress, cold sweat or facial pallor after eating/touching chicken/eggs.
    If you have liver disorder or have a history of it.
    If you have skin disease on injection site.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, inject into the knee joint once a week for 3 consecutive times.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash and injection site numbness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general itching, hives, uncomfortable feeling in the throat, breathing difficulty [shock, anaphylactoid symptoms]
  • fever, pain or swelling of injection site [arthritis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep at rest after injection. Avoid performing prolonged weight-bearing activity or intense exercise.
  • Keep the injection site clean on the day of injection to prevent bacterial invasion and protect from infection.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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