くすりのしおり

Internal
Published: 8/2016

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CADETHIA COMBINATION TABLETS LD "ASKA"
 Active ingredient:
Candesartan cilexetil
Hydrochlorothiazide
 Dosage form:
very pale yellow tablets, major axis: 8.6 mm, minor axis: 5.1 mm, thickness: approx. 3.0 mm
 Print on wrapping:
(Face)カデチア配合錠LD「あすか」, AK302, カデチアLD
(Back)CADETHIA COMBINATION TABLETS LD「ASKA」, カンデサルタン4mg, ヒドロクロロチアジド6.25mg, カデチア配合錠, LD

Effects of this medicine

This medicine lowers blood pressure by antagonism to angiotensin II receptor and by increasing urine output via inhibition of sodium and water reabsorption in the kidney.
It is usually used for treatment of hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you ever experienced any allergic reaction (itch, rash etc.) to any medicine.
    If you scarcely void urine; are on hemodialysis; or have electrolyte imbalance (abnormal blood sodium, potassium, calcium levels), renal disease, liver disorder, coronary arterial sclerosis, cerebral arterial sclerosis, diarrhea/vomiting, or hyperparathyroidism.
    If you are on low-salt diet, in a post-sympathectomy state, in a preoperative state.
    If you or any one among your parents and siblings have gout/diabetes mellitus.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet at a time, once a day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is 8 hours or less before taking the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • As dizziness and light-headedness may appear due to lowering of blood pressure, take extra care when working at heights or operating dangerous machinery such as driving a car.
  • Caution should be exercised as alcohol drinking may intensify orthostatic hypotension (dizziness on standing up).

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, photosensitivity, eczema, hives, itching, breathing difficulty, hot flush, dizziness, palpitation, glow, light-headedness, dizziness on standing up, headache, nausea, stomatitis, taste abnormality, constipation, dry mouth, malaise, frequent urination, edema, cough, erectile dysfunction and abnormal vision. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • swelling of face/lips/tongue/throat [angioedema]
  • feeling cold, nausea, loss of consciousness [shock, syncope, loss of consciousness]
  • decreased urination output, generalized swelling, headache [acute renal failure]
  • muscle weakness, numbness of hands/feet and lips, paralysis of limbs [hyperkalemia]
  • general dullness, loss of appetite, nausea [hyponatremia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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