くすりのしおり

Injection
Revised: 5/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
Apnission for Intravenous Injection 15mg
 Active ingredient:
Aminophylline hydrate
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine acts on the site that controls respiration in brain (respiratory center).
It is usually used to treat apnea in premature delivery/low birth weight infants.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If the mother/infant has previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If the infant has convulsion or fever. If the mother has used xantines such as theophylline during pregnancy. If the mother uses xantines such as theophylline during breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, inject this medicine intravenously slowly in 2 to 3 divided doses a day.
  • Treatment period will be decided according to the frequency or duration of apnea attack, or the symptoms.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include newborn nausea, tachycardia, convulsion, excitation, abdominal bloating and coffee residual-like substance. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • hives, facial pallor, cold sweat, dizziness, breathing difficulty, shortness of breath [shock, anaphylactic shock]
  • convulsion, semi-consciousness, loss of conscinousness [convulsion, consciousness disorder, acute encephalopathy]
  • muscle pain, weakness of limbs, red urine [rhabdomyolysis]
  • chest/abdominal pain, black stool, blood vomiting [gastrointestinal bleeding]
  • shortness of breath, facial pallor, palpitation [pure red-cell aplasia]
  • general malaise, nausea, loss of appetite, general itching, yellowing of the white of eyes or body [liver dysfunction, jaundice]
  • rapid breathing, thirst, increased urine output, general malaise [tachypnea, hyperglycemia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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