くすりのしおり

Internal
Revised: 9/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BENIDIPINE HYDROCHLORIDE TABLETS 4mg "TANABE"
 Active ingredient:
Benidipine hydrochloride
 Dosage form:
yellow tablet, diameter: 7.2 mm, thickness: 3.2 mm
 Print on wrapping:
(Face)ベニジピン塩酸塩4mg「タナベ」, ベニジピン塩酸塩, 4, TG120
(Back)Benidipine Hydrochloride4, ベニジピン塩酸塩4mg「タナベ」, 4mg, 高血圧症・狭心症の薬です

Effects of this medicine

This medicine blocks calcium inflow into cell which causes vasoconstriction and consequently dilates constricted vessels to decrease blood pressure. It also dilates vessels of the heart to prevent developing anginal attacks (chest pain which mostly occurs in the heart).
It is usually used to treat hypertension, renal parenchymal hypertension and angina pectoris.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.If you have : cardiac disease, liver disorder or hypotension.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • Hypertension and renal parenchymal hypertension: In general, for adults, take 0.5 to 1 tablet (2 to 4 mg of the active ingredient) at a time, once a day, after breakfast. The dosage may be adjusted according to the age or symptoms. If the effect is insufficient, the dosage may be increased up to 2 tablets (8 mg) at a time, once a day. In case of severe hypertension, take 1 to 2 tablets (4 to 8 mg) at a time, once a day, after breakfast.
    Angina pectoris: In general, for adults, take 1 tablet (4 mg of the active ingredient) at a time, twice a day, after breakfast and dinner. The dosage may be adjusted according to the age or symptoms.
    Strictly follow the instructions in any case.
  • If you miss a dose, take the missed dose as soon as you remember. After taking the medicine, wait about 8 hours for hypertension, and about 5 hours for angina pectoris to take the next dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness/light-headedness due to decreased blood pressure. Pay close attention when you drive a car, work at heights or operate dangerous machinery.
  • Do not take grapefruit juice and the medicine together as it may intensify the effect of the medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, photosensitivity, gynecomastia, palpitation, facial hot flush and headache. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, loss of appetite, yellowing of the skin and the white of eyes [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist or the medical institution staff how to discard.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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