くすりのしおり

Injection
Published: 5/2020

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
EYLEA IVT inj. KIT 40mg/mL [neovascular glaucoma]
 Active ingredient:
Aflibercept (genetical recombination)
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine inhibits vascular endothelial growth factor (VEGF) which is involved in formation and growth of iris and angle neovascularization and improves aqueous humor outflow resistance by regressing iris and angle neovascularization. As a result, it lowers elevated pressure in the eye.
It is usually used to treat neovascular glaucoma.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: infection in/around the eyes or suspected of them, intraocular inflammation, glaucoma, ocular hypertension, or history of stroke or transient ischemic attack.
    If you wear contact lenses.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, this medicine is injected once in the eye (vitreous body). If necessary, reinjection may be performed. Whether to reinject is determined depending on your symptoms and therapeutic effects while regularly measuring intraocular pressure, but the dosing interval should be at least 1 month apart.
  • This medicine may be used in combination with other treatments for long-term management of intraocular pressure.

Precautions while taking this medicine

  • This medicine may cause blurred vision temporarily after the injection. Do not operate machinery or drive a car until these symptoms recover.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include conjunctival bleeding, injection site pain and eye pain. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, see your doctor immediately.
  • eye pain, sensation of heat in the eyes, worsening of bloodshot eyes, myodesopsia (seeing objects that look like black insects moving) [eye disorder such as intraocular inflammation, increased intraocular pressure, vitreous detachment]
  • decreased consciousness, one-sided paralysis, speaking difficulty [stroke]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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