くすりのしおり

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Published: 6/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ADAPALENE GEL 0.1% "TOKO"
 Active ingredient:
Adapalene
 Dosage form:
white smooth gel (It may contain lumps of particles.)
 Print on wrapping:

Effects of this medicine

This medicine prevents pores from clogging by inhibiting differentiation of epidermal keratinocytes, and then it suppresses formation of comedones. Thereby, it is effective in reducing non-inflammatory lesions [closed comedones (whiteheads), open comedones (blackheads)] and further inflammatory lesions (papules).
It is usually used for the treatment of acne vulgaris.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding. If you desire or became pregnant during treatment, discontinue using this medicine and tell your doctor.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, after washing your face before bedtime, apply this medicine to acnes, once a day. Strictly follow the instructions.
  • After washing your face, wipe off any moisture before using.
  • Use this medicine only for facial acne.
  • Do not apply it to affected skin areas accompanied with cuts, scratches and eczema.
  • Use this medicine to affected parts except eyes, lips, nostrils and mucus membrane.
  • When used around the eyes, take care so that this medicine does not get into your eyes. If it gets into your eyes, wash out your eyes with water immediately.
  • If you miss a dose the day before, use a suitable amount of this medicine before bedtime following the instructions. You should not use it twice a day or two doses at one time.
  • If you accidentally use more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop using this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Avoid excessive exposure to ultraviolet rays, such as sunlight and tanning lamps.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include dry skin, discomfort feeling of skin, skin exfoliation, erythema, itch and eczema. These adverse reactions mostly occur within the first 2 weeks of use, and they are usually mild and temporary. However, if the symptoms worsen or do not improve, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
No pertinent entries.
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture. Do not freeze it.
  • Discard the remainder. Do not store them. For disposal methods, consult the pharmacy or the medical institution from which you have received the medicine.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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