くすりのしおり

Injection
Published: 3/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
NerBloc for Intramuscular Injection 2500 Units
 Active ingredient:
Botulinum toxin type B
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine suppresses muscle tension.
It is usually used to treat cervical dystonia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines. If you are treated with an injection of Botulinum toxin at other medical institution. If you have diseases such as generalized muscle weakness. If you have respiratory dysfunction, or severe muscle weakness or atrophy. If you are taking muscle-relaxing medicine or medicine acting on muscle relaxation.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, inject this medicine intramuscularly. If you have multiple sites with muscle tension, inject separately.
    If its effect is insufficient or recurrent symptoms appear, this medicine may be re-injected. However, avoid re-injecting within 2 months.
  • Effects of this medicine usually continue for 3 to 4 months. As the effects gradually disappear and return to the state prior to the injections, inject this medicine repeatedly at an interval of 3 to 4 months.

Precautions while taking this medicine

  • This medicine may cause adverse drug reactions such as lassitude, muscle weakness, dizziness and reduced visual acuity. Pay attention when operating machinery such as driving a car.
  • If you had any restrictions on your daily activities before treatment, avoid performing physical exertion with excessive muscular contraction and resume activities gradually after starting an injection of this medicine.
  • Since similar medicines have been reported to have toxicity, male patients and female patients who have a possibility of pregnancy should use adequate contraception.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include swallowing disorder, thirst and dry mouth. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, respiratory distress on exertion, shortness of breath [respiratory distress]
  • skin itching, hives, hoarse voice, sneezing, itching throat, breathing difficulty, palpitation, confused consciousness  [anaphylactoid symptoms]
  • difficulty in swallowing foods [swallowing disorder]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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