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海外渡航情報
DAIICHI SANKYO COMPANY, LIMITED
Internal
Revised: 3/2019
The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
AMPLIT TABLETS 25mg
Active ingredient:
Lofepramine hydrochloride
Dosage form:
white tablet, diameter: 7.9 mm, thickness: 4.8 mm
Print on wrapping:
アンプリット25mg, Amplit 25mg, D104
Effects of this medicine
This medicine is a tricyclic antidepressant which improves depression and depressive state by inhibiting monoamine uptake into presynaptic terminals in brain neuron (hypothalamus/cerebral limbic system).
It is usually used to treat depression and depressive state.
Before using this medicine, be sure to tell your doctor and pharmacist
If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have glaucoma.
If you are in early recovery period of myocardial infarction.
If you are pregnant or breastfeeding.
If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
Your dosing schedule prescribed by your doctor is
(( to be written by a healthcare professional))
In general, for adults, start with 1 tablet (25 mg as lofepramine) at a time, in 2 to 3 divided doses. The dosage may be gradually increased up to 6 tablets (150 mg) a day. The dosage may be adjusted according to the age or symptoms.Strictly follow the instructions.
If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
Do not stop taking this medicine unless your doctor instructs you to do so.
Precautions while taking this medicine
This medicine may cause sleepiness or ataxia . Avoid operating dangerous machinery, such as driving a car.
Pay attention that alcohol may intensify medicinal effects.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include dry mouth, constipation, sleepiness, insomnia, loss of appetite, nausea and lightheadedness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
stiff muscles, difficulty swallowing, fever [neuroleptic malignant syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.
Storage conditions and other information
Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
Discard the remainder. Do not store them.
For healthcare professional use only :
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For further information, talk to your doctor or pharmacist.
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