くすりのしおり

Injection
Revised: 2/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
SLONNON HI INJECTION 10mg/2mL [chronic arterial occlusion]
 Active ingredient:
Argatroban hydrate
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine inhibits the blood coagulation enzyme (thrombin), making it harder to clot blood and prevents thrombus formation in the blood vessels.
It is usually used to improve ulcer, pain and cold feeling of limbs caused by poor blood flow due to arteriosclerosis.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: bleeding (thrombocytopenic purpura, bleeding tendency due to vascular disorder, hemophilia or other coagulopathy, menstrual period, gastrointestinal bleeding, urinary tract bleeding, hemoptysis, pregnant woman with genital bleeding such as miscarriage/premature birth/postpartum, etc.), a possibility of bleeding (gastric ulcer, duodenal ulcer, colitis, bacterial endocarditis, history of cerebral hemorrhage, hypertension, diabetes mellitus, etc.), liver disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, this medicine is administered by intravenous infusion twice a day over a period of two to three hours.
  • The treatment period with this medicine depends on your symptoms, but it should not exceed 4 weeks.

Precautions while taking this medicine

  • When this medicine is injected, blood function is examined.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include prolonged coagulation time, bleeding, bloody urine, anemia, rash, itch, hives, vomiting, diarrhea, headache, pain in feet and feeling of warmth. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • persistent headache, unilateral or bilateral paralysis, abdominal pain, vomiting of blood, bloody stool [cerebral bleeding, gastrointestinal bleeding]
  • hives, pale face, breathing difficulty [shock, anaphylactic shock]
  • general malaise, loss of appetite, yellowing of the skin or white eyes [fulminant hepatitis, liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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