くすりのしおり

Injection
Published: 3/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BOSMIN INJECTION 1mg [for adjunctive treatment of acute hypotension]
 Active ingredient:
Adrenaline
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine relaxes bronchial muscle, increases heart rate and enhances myocardial contraction resulting in an increased cardiac output. It also has both vasoconstrictive and vasodilatory actions. It dilates coronary arteries and constricts dermal microvessels to increase peripheral vascular resistance and raise blood pressure. It enhances action of local anesthesia and prolongs its effect.
It is usually used for remission of bronchial spasm associated with bronchial asthma or whooping cough, adjunctive treatment of acute hypotension/shock or cardiac arrest, prolongation of action of local anesthetics, prevention and treatment of local bleeding during surgery.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have predisposition of increased intraocular pressure.
    If you have arteriosclerosis, hyperthyroidism, diabetes mellitus, arrhythmia, psychoneurosis, addiction to cocaine, heart disease, hypertension, or emphysema.
    If you are receiving spinal anesthesia.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For remission of bronchial spasm associated with bronchial asthma or whooping cough: In general, inject subcutaneously or intramuscularly, once.
    For adjunctive treatment of acute hypotension/shock associated with diseases and conditions, or cardiac arrest: In general, for resuscitation use, inject intravenously as slowly as possible. If necessary, repeat administration at 5 to 15 minute intervals.
    For prolongation of action of local anesthetics: In general, this medicine is added to a vasoconstrictor-free local anesthetic before use.
    For prevention and treatment of local bleeding during surgery: In general, this medicine should be administered solely or added to local anesthetic and administered as a local injection.
  • The treatment period with this medicine depends on your response to the treatment.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include palpitation, headache, dizziness, anxiety, tremor, hypersensitivity symptoms, nausea/vomiting, heat sensation and sweating. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • abnormally increased blood pressure, palpitations after exercise, respiratory distress, easy breathing in upright position than when lying down, nausea [pulmonary edema]
  • respiratory difficulty, respiratory difficulty on exertion [respiratory distress]
  • tachycardia, arrhythmia, palpitation, chest anguish, cardiac arrest [cardiac arrest]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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