くすりのしおり

Injection
Revised: 3/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
VELCADE Injection 3mg
 Active ingredient:
Bortezomib
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine selectively inhibits proteasome to suppress proliferation of cancer cells.
It is usually used to treat multiple myeloma, mantle cell lymphoma, primary macroglobulinemia and lymphoplasmacytic lymphoma.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have a history of pulmonary disorder such as interstitial pneumonia and pulmonary fibrosis.
    If you have hepatic disorder, symptoms of peripheral neuropathy (numbness/pain/hot flush in limbs), dehydration or diabetic neuropathy.
    If you have a history or risk factor of cardiac disorder.
    If you are hepatitis B virus carrier, or negative for HBs antigen and positive for HBc antibody or HBs antibody.
    If you have symptoms or have a history of faint.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, inject intravenously or subcutaneously once a day. At least 72 hours should elapse between consecutive doses.
  • The treatment span depends on the effect of the medicine after using it for a certain period.

Precautions while taking this medicine

  • Avoid performing dangerous operations such as driving a car after injection, since this medicine may cause fatigue, dizziness, dizziness on standing up, faint or focus disorder.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include anemia, localized injection site reaction due to subcutaneous injection (erythema/pain/itching at injection site), loss of appetite, diarrhea, rash. constipation, nausea, fever, decreased body weight, peripheral neuropathy, dullness, vomiting, abnormal hepatic function, hypoesthesia, herpes zoster, nerve pain, fatigue and asthenia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • shortness of breath, chest distress, cough [pulmonary disorder]
  • palpitation/shortness of breath, chest pain, leg edema [cardiac disorder]
  • restless leg, difficulty in writing, feeling of stepping on an object with many bumps [peripheral nerve disorder]
  • fever, bleeding tendency, fatigability/shortness of breath [bone marrow depression]
  • constipation, abdominal pain, abdominal bloating, loss of appetite [ileus]
  • decreased urine output/bloody urine, decreased consciousness, spasm [tumor lysis syndrome]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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