くすりのしおり

Internal
Published: 12/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CARVEDILOL Tablets 10mg "Me"
 Active ingredient:
Carvedilol
 Dosage form:
yellow tablet, diameter: 6.8 mm, thickness 3.6 mm
 Print on wrapping:
カルベジロール10mg「Me」, カルベジロール10, MeP014, CARVEDILOL10mg「Me」, meiji, Meファルマ

Effects of this medicine

This medicine decreases blood pressure by blocking B-receptors and a1-receptors. It also suppresses excess activity of the heart and improves cardiac functions.
It is usually used to treat essential hypertension (mild to moderate), renal parenchymal hypertension, angina pectoris, chronic heart failure (due to ischemic heart disease or dilated cardiomyopathy) and tachycardiac atrial fibrillation.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have bronchial asthma, risk ob bronchospasm, diabetic ketoacidosis, metabolic acidosis, bradycardia, atrioventricular block, sinoatrial block, cardiogenic shock, heart failure, pheochromocytoma or peripheral circulatory disorder.
  • If you are pregnant, breastfeeding or possibly pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For essential hypertension (mild to moderate) and renal parenchymal hypertension: In general, for adults, take 10 to 20 mg of the active ingredient at a time, once a day. However, the dosage may be adjusted according to the age or symptoms.
    For angina pectoris: In general, for adults, take 20 mg of the active ingredient at a time, once a day. However, the dosage may be adjusted according to the age or symptoms.
    For chronic heart failure (due to ischemic heart disease or dilated cardiomyopathy): In general, for adults, start with 1.25 mg of the active ingredient at a time, twice a day after meals. If this medicine is tolerated (or taken without any problem), the dosage may be gradually increased in a stepwise manner at intervals of at least 1 week. If not, the dosage may be reduced. The dosage must be increased or decreased step by step, with 1.25 mg, 2.5 mg, 5 mg or 10 mg taken at a time, twice a day after meals. In general, as a maintenance dose, take 2.5 mg to 10 mg at a time, twice a day after meals. The starting dose may be even lower according to the age or symptoms, and the maintenance dose may be adjusted according to responsiveness.
    For tachycardiac atrial fibrillation: In general, for adults, start with 5 mg of the active ingredient at a time, once a day, and if its effect is insufficient, the dosage may be gradually increased to 10 mg at a time, once a day, and then to 20 mg at a time, once a day. The dosage may be adjusted according to the age or symptoms, but the maximum dose is 20 mg at a time, once a day.
    This medicine contains 10 mg of the active ingredient in a tablet. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness/light headedness. Avoid operating dangerous machinery, such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include dizziness, palpitation, bradycardia, hypotension, worsening of diaberes mellitus, malaise and rash.
If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • shortness of breath, dizziness, syncope [severe bradycardia, shock, complete atrioventricular block, heart failure, cardiac arrest]
  • general malaise, loss of appetite, yellow discoloration of the skin and the white of eyes  [liver dysfunction, jaundice]
  • general malaise, decreased urine output, edema of linbs and face [acute renal failure]
  • fever, general malaise, rash and redness of skin/ eye / mouth  [toxic epidermal necrolysis, mucocutaneous ocular syndrome]
  • respiratory distress, hives, swelling around eyes and lips [anaphylaxis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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