くすりのしおり

Internal
Published: 12/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
CARVEDILOL Tablets 1.25mg "Me"
 Active ingredient:
Carvedilol
 Dosage form:
yellow tablet, major axis: 10.1 mm, minor axis: 5.1 mm, thickness: 3.2 mm
 Print on wrapping:
カルベジロール1.25mg「Me」, MeP012, 1.25mg, CARVEDILOL1.25mg「Me」, meiji, Meファルマ

Effects of this medicine

This medicine shows vasodilating effects by blocking B-receptors and a1-receptors to maintain and decrease vascular resistance, thereby improving heart pump function and providing sufficient blood flow to the body to improve cardiac functions.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    if you have bronchial asthma, risk of bronchospasm, diabetic ketoacidosis, metabolic acidosis, bradycardia, atrioventricular block, sinoatrial block, cardiogenic shock, heart failure, pheochromocytoma or peripheral circulatory disorder.
  • If you are pregnant, breastfeeding or possibly pregnant.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with 1 tablet (1.25 mg of the active ingredient) at a time, twice a day after meals. If this medicine is tolerated (or taken without any problem), the dosage may be gradually increased in a stepwise manner at intervals of at least 1 week. If not, the dosage may be reduced. The dosage must be increased or decreased step by step, with 1 tablet (1.25 mg), 2 tablets (2.5 mg), 4 tablets (5 mg) or 8 tablets (10 mg) taken at a time, twice a day after meals. In general, as a maintenance dose, take 2 to 8 tablets (2.5 mg to 10 mg) at a time, twice a day after meals. The starting dose may be even lower according to the age or symptoms, and the maintenance dose may be adjusted according to responsiveness. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness/light headedness. Avoid operating dangerous machinery, such as driving a car.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include,dezziness, palpitation, tachycardia, increased dizziness, palpitation, bradycardia, hypotension, worsening of diabetes mellitus, mallitus, malaise nad rash. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • shortness of breath, dizziness, syncope [severe bradycardia, shock, complete atrioventricular block, heart failure, cardiac arrest]
  • general malaise, loss of appetite, yellow discoloration of the skin and the white of eyes  [liver dysfunction, jaundice]
  • general malaise, decreased urine output, edema of limbs and face  [acute renal failure]
  • fever, general malaise, rash and, redness of skin/ eye/ mouth  [toxic epidermal necrolysis, mucocutaneous ocular syndrome]
  • respiratory distress, hives, swelling around eyes and lips  [anaphylaxis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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