くすりのしおり

Internal
Published: 4/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ISOBIDE syrup 70%
 Active ingredient:
Isosorbide
 Dosage form:
colorless to pale yellowish brown solution
 Print on wrapping:

Effects of this medicine

This medicine increases plasma osmotic pressure to show effects of lowering intracranial pressure/intraocular pressure/intra-aural lymphatic pressure or diuretic effect.
It is usually used for the purpose of lowering the pressure in intracranial hypertension resulting from brain tumor or head injury, diuresis in case of kidney/ureteral stone, lowering intraocular pressure in glaucoma, and the treatment of Meniere's disease.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: intracranial hematoma.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For the purpose of lowering brain pressure/intraocular pressure or diuresis: In general, for adults, take 70 to 140 mL (49 to 98 g of the active ingredient) a day in two to three divided doses. The dosage should be adjusted according to your disease and symptoms.
    For the treatment of Meniere's disease
    : Standard daily dose is 1.5 to 2.0 mL/kg (1.05 to 1.4 g of the active ingredient) of the body weight. In general, for adults, take 30 to 40 mL (21 to 28 g) at a time, three times a day. The dosage should be adjusted according to your symptoms.
    If it is hard to drink, mix it with as much of cold water and take it. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, diarrhea, vomiting, rash and erythema. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • rash, breathing difficulty, palpitation [shock, anaphylactoid symptoms]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • After opening, screw the cap on tightly and store in cold place.
  • It may discolor in some environments, which has no affect on the effects and quality of the product.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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