くすりのしおり

Internal
Revised: 2/2014

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LEVOTOMIN Tablets 5mg
 Active ingredient:
Levomepromazine maleate
 Dosage form:
white tablet, diameter 7.1 mm, thickness 2.8 mm
 Print on wrapping:
レボトミン5mg, LEVOTOMIN5mg

Effects of this medicine

This medicine blocks receptors for dopamine and serotonin, neurotoransmitters, to relieve anxiety and tension and to stabilize unstable mental status.
It is usually used for treatment of anxiety and tension associated with schizophrenia, mania, and/or depression.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you are patient with suspected brain disorder (encephalitis, brain tumor, aftereffects of head trauma).
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 25 mg to 200 mg of levomepromazine a day, in several divided doses. It should be adjusted according to your disease, age and symptoms. This preparation containes 5 mg of levomepromazine in a tablet. Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause drowsiness, lack of attentiveness, concentration or ability of reflexive motion. Avoid driving a car or operating machinery requiring alertness.
  • Alcohol may intensify the effects of the medicine. Be careful when drinking alcohol.
  • This medicine may enhance the toxicity of organophosphate insecticides and cause narrowing of pupils, slow pulse rate, breathlessness, diziness or fatigability. Be careful with handling such agents.

Possible adverse reactions to this medicine

Reported adverse reactions include thrombocytopaenic purpura (fever, malaise, bruise), hypersensitivity, photosensitivity, and liver disorder (general malaise, loss of appetite, yellowing of the skin or the whites of the eyes) . If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • fever (over 37.5 degree C), tremor in limbs, stiff muscles [neuroleptic malignant syndrome]
  • dizziness, palpitation, chest discomfort/chest pain [sudden death]
  • sore throat, fever, bleeding from the nose or the gums [aplastic anaemia, agranulocytosis, decreased white blood cells]
  • abdominal distension/abdominal pain, constipation, nausea/vomiting [paralytic ileus]
  • involuntary movements of mouth, toungue or jaw, as if chewing, rolling of the eyes, involuntary pulling of the neck [tardive dyskinesia, tardive dystonia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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