くすりのしおり

Internal
Revised: 10/2013

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
LORELCO Tablets 250 mg
 Active ingredient:
Probucol
 Dosage form:
white to slightly yellowish white tablet, diameter 11.1 mm, thickness 4.5 mm
 Print on wrapping:
(Front) ロレルコ錠 250 mg, ロレルコ錠, Otsuka, 250 mg, OG23 (Back) ロレルコ錠 250 mg, Lorelco tab 250 mg

Effects of this medicine

This medicine lowers cholesterol in the blood by stimulating catabolic excretion of cholesterol into the bile and inhibiting cholesterol synthesis.
It is usually used in the treatment of hyperlipidemia (including familial hypercholesterolemia and xanthoma).

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reaction (itch, rash, etc.) to any medicines.
    If you have ventricular arrhythmia.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and food.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 1 tablet (250 mg of the active ingredient) at a time, twice daily after meals. The dosage may be adjusted according to your disease, age or symptoms. For the treatment of familial hypercholesterolemia, the daily dosage may be increased up to 4 tablets (1,000 mg). Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Strictly follow diet and exercise therapy instructed by your doctor.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include diarrhea/loose stool, nausea/vomiting, rash, and itch. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • palpitation, chest pain, loss of consciousness [ventricular arrhythmia, syncope]
  • hematemesis, melena, black stool [gastrointestinal bleeding]
  • numbness of limbs, weakness or muscle atrophy of limbs, pain [peripheral neuritis]
  • muscular pain, feeling of weakness, reddish brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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