くすりのしおり

Internal
Revised: 6/2012

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
THYRADIN-S TABLETS 50mcg
 Active ingredient:
Levothyroxine sodium hydrate
 Dosage form:
white tablet, diameter: 6.5 mm, thickness: 2.4 mm
 Print on wrapping:
(face) チラーヂンS50μg, TZ224, 50μg
(back) THYRADIN-S50μg, チラーヂンS50μg

Effects of this medicine

This medicine is a thyroid hormone preparation and replaces thyroid hormone which is deficient due to thyroid disorder or a surgery.
It is usually used in the treatment of hypothyroidism (primary or hypophyseal) myxedema, cretinism, and goiter.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: myocardial infarction, cardiovascular or vascular disorders, adrenocortical insufficiency or pituitary gland disorder.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 25 to 400 μg of levothyroxine sodium at a time, once daily. In general, start with taking 25 to 100 μg and the dose will be increased gradually, however, the maintenance dose is 100 to 400 μg at a time, once daily. The dosage may be adjusted according to the age or symptoms.
    This preparation contains 50 μg of levothyroxine sodium in a tablet.
    Strictly follow the instructions.
  • If you miss a dose, take a dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include hypersensitivity (rash, itch, etc.). If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • chest pain, pressure feeling, constricted feeling  [angina pectoris]
  • general malaise, loss of appetite, yellowing in skin and white of eyes  [hepatic dysfunction, jaundice]
  • general malaise, hypotension, decreased urine output  [adrenal crisis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask the pharmacist and medical facility how to discard them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.

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