くすりのしおり

Internal
Published: 12/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
PRAVASTATIN Na Tablets 5 "KN"
 Active ingredient:
Pravastatin sodium
 Dosage form:
white tablet, diameter: approx. 6.6 mm, thickness: approx. 2.2 mm
 Print on wrapping:
(Face)プラバスタチン Na 5「KN」, 5 mg, KN 253, プラバスタチン Na「KN」
(Back)PRAVASTATIN Na 5「KN」, プラバスタチン Na「KN」,5 mg, 高コレステロール血症の薬

Effects of this medicine

This medicine lowers cholesterol in the blood by inhibiting cholesterol synthetase (HMG-CoA reductase) in the liver.
It is usually used to treat hyperlipidemia or familial hypercholesterolemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 tablets (10 mg of the active ingredient) a day, in 1 to 2 divided doses. The dosage may be adjusted according to the age or symptoms. If symptoms are severe, the dosage may be increased up to 4 tablets (20 mg) a day. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Make sure you have a proper diet and exercise therapy.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, eczema, hives, itch, erythema, loss of hair, photosensitivity and anemia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • muscle pain of limbs, lassitude, reddish brown urine [rhabdomyolysis]
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva [liver disorder]
  • nose bleeding, gum bleeding, limb subcutaneous bleeding [thrombocytopenia]
  • fever, dry cough, respiratory distress [interstitial pneumonia]
  • muscle stiffness, pain, muscle weakness [myopathy, immune-mediated necrotizing myopathy]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.