くすりのしおり

Internal
Published: 10/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
TICLOPIDINE HYDROCHLORIDE Tablets 100mg "YD"
 Active ingredient:
Ticlopidine hydrochloride
 Dosage form:
white tablet, diameter: approx. 8.2 mm, thickness: approx. 4.1 mm
 Print on wrapping:
(Face)チクロピジン塩酸塩錠100 mg「YD」, 100 mg, チクロピジン
(Back)TICLOPIDINE HYDROCHLORIDE 100 mg, チクロピジン塩酸塩錠100 mg「YD」, 100 mg, 抗血小板剤, YD 168

Effects of this medicine

This medicine controls the action of platelets in blood and suppresses platelet aggregation and adhesion, leading to improvements in peripheral circulatory disorder.
It is usually used to treat thrombus/embolus and improve blood flow disturbance and ischemic symptoms.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: bleeding (hemophilia, capillary fragility, gastrointestinal ulcer, bleeding of urinary tract, hemoptysis, vitreous bleeding, etc.), liver disorder or leukopenia.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For thrombus/embolus associated with vascular surgery or extracorporeal circulation and blood flow disturbance: In general, for adults, take 2 to 3 tablets (200 mg to 300 mg of the active ingredient) a day, in 2 to 3 divided doses after meals.
    For chronic arterial occlusion: In general, for adults, take 3 to 6 tablets (300 mg to 600 mg) a day, in 2 to 3 divided doses after meals.
    For ischemic cerebrovascular disorder: In general, for adults, take 2 to 3 tablets (200 to 300 mg) a day, in 2 to 3 divided doses after meals. However, may be taken 2 tablets (200 mg) once a day.
    For after subarachnoid hemorrhage surgery: In general, for adults, take 3 tablets (300 mg) a day, in 3 divided doses after meals.
    In any case, the dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Once you start bleeding, it will not stop easily. If you have prolonged bleeding or serious injury, consult with your doctor immediately.
  • If surgery or tooth extraction is scheduled, make sure to tell your doctor that you are taking this medicine.
  • For the first 2 months, visit your doctor once every 2 weeks as a rule because regular blood tests are needed for early detection of serious adverse reactions. Blood tests will also be performed on a regular basis after the first 2 months.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nose bleeding, subcutaneous bleeding, loss of appetite and nausea. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • malaise, loss of appetite, purpura [thrombotic thrombocytopenic purpura]
  • fever, sore throat, malaise [agranulocytosis]
  • nausea, loss of appetite, malaise [severe liver disorder]
  • palpitation, shortness of breath, gum bleeding/ subcutaneous bleeding [blood disorders such as pancytopenia including aplastic anemia, pure red-cell aplasia and thrombocytopenia]
  • headache, consciousness disorder, melena [bleeding (intracranial bleeding such as cerebral bleeding, severe bleeding such as gastrointestinal bleeding]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.