くすりのしおり

Internal
Published: 2/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
BENZBROMARONE Tablets 50mg "Kyorin"
 Active ingredient:
Benzbromarone
 Dosage form:
white to pale yellow tablet, diameter: 8.1 mm, thickness: 2.1 mm
 Print on wrapping:
(Face)ベンズブロマロン 50 mg「杏林」, ベンズブロマロン, 50, PH 308
(Back)Benzbromarone 50 mg, 50, 尿酸排泄薬, ベンズブロマロン 50 mg「杏林」

Effects of this medicine

This medicine promotes excretion of uric acid into the urine by suppressing reabsorption of uric acid in the renal tubules in order to improve hyperuricemia.
It is usually used to improve hyperuricemia in patients with gout or hypertension with hyperuricemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: liver disorder or kidney stones.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • For gout: In general, for adults, take 25 mg or 50 mg of the active ingredient at a time, once a day. Then take 1 tablet (50 mg of the active ingredient) at a time, 1 to 3 times a day as the maintenance dose. The dosage may be adjusted according to the age or symptoms.
    For hypertension with hyperuricemia: In general, for adults, take 1 tablet (50 mg) at a time, 1 to 3 times a day. The dosage may be adjusted according to the age or symptoms.
    This preparation contains 50 mg of the active ingredient in a tablet. In any case, strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Liver function tests are carried out on a regular basis for the first six months after the start of treatment. May also be performed on a regular basis after the sixth month.
  • Uric acid stones, bloody urine and renal colic due to these stones may develop easily if you have acidic urine. To prevent these symptoms, take plenty of water to increase urinary volume and alkalize urine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include itch, rash, hives, facial redness, erythema and jaundice. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva  [severe liver disorder]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.