くすりのしおり

Internal
Published: 2/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ALLOPURINOL Tablets 100mg "Kyorin"
 Active ingredient:
Allopurinol
 Dosage form:
white tablet, diameter: 9.6 mm, thickness: 3.9 mm
 Print on wrapping:
(Face)アロプリノール錠100 mg「杏林」, アロプリノール, 100, PH 113
(Back)Allopurinol 100 mg, 100, 高尿酸血症治療剤, アロプリノール 100 mg「杏林」

Effects of this medicine

This medicine inhnbits the production of uric acid in the body by inhibiting xanthine oxidase, resulting in decreased amount of uric acid in the blood and urine.
It is usually used to improve hyperuricemia in patients with gout or hypertension associated with hyperuricemia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 2 to 3 tablets (200 to 300 mg of the active ingredient) a day, in 2 to 3 divided doses, after meals. The dosage may be adjusted according to the age or symptoms. Strictly follow the instructions.
  • Gout attack (pain) may be temporarily intensified when you start taking this medicine. However, do not change the dose or stop taking this medicine on your own unless your doctor instructs you to do so. If such a symptom occurs, consult with your doctor.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • When taking this medicine, take plenty of water and try to increase the amount of urine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itch, joint pain, anemia, purpura (bruise), lymphadenopathy and abnormal renal function. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • rash, erythema, blister [serious skin disorder such as toxic epidermal necrolysis/ muco-cutaneo-ocular syndrome/ exfoliative dermatitis, hypersensitivity vasculitis]
  • rash, fever, sore throat [drug-induced hypersensitivity syndrome]
  • pale face, cold sweat, respiratory distress [shock, anaphylaxis]
  • general malaise, headache, gum bleeding/ subcutaneous bleeding [aplastic anemia, pancytopenia, agranulocytosis, thrombocytopenia]
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva [severe liver dysfunction such as fulminant hepatitis, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.