くすりのしおり

Internal
Published: 3/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
GLIMEPIRIDE Tablets 0.5mg "FFP"
 Active ingredient:
Glimepiride
 Dosage form:
white tablet, diameter: 4.5 mm, thickness: 1.9 mm
 Print on wrapping:
(Face)グリメピリド 0.5 mg「FFP」, 糖尿病用薬
(Back)Glimepiride 0.5 mg「FFP」, グリメピリド, 0.5 mg, 糖尿病用薬

Effects of this medicine

This medicine acts pancreatic β cells and promotes insulin secretion, resulting in decreased levels of blood glucose.
It is usually used to treat type 2 diabetes mellitus.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have: ketosis, diabetic coma or precoma, insulin-dependent diabetes mellitus, liver or renal disorder, infections, external injury or gastrointestinal disorder such as diarrhea/vomiting.
    If you are in the pre-/post-operative period.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, start with 1 to 2 tablets (0.5 to 1 mg of the active ingredient) a day, in 1 to 2 divided doses, in the morning or in the morning and evening, before or after meals. In general, the maintenance dose is 2 to 8 tablets (1 to 4 mg) a day and the dosage may be adjusted as necessary. However, the daily dose will not exceed 12 tablets (6 mg). Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • Hypoglycemic symptom may occur. Be aware of working at heights or operating dangerous machinery such as driving a car.
  • If hypoglycemic symptoms (sweating, chills, palpitation, dizziness, headache, shivering of limbs, hunger, weakness, consciousness disorder) occur, take sugar. If you are taking α-glucosidase inhibitors (acarbose, voglibose, etc.) in combination with this medicine, take glucose in case of hypoglycemic symptom appearance.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include nausea, diarrhea and dizziness. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • lassitude, a sense of hunger, sweat [hypoglycemia]
  • general malaise, headache, gum bleeding/ subcutaneous bleeding [pancytopenia, agranulocytosis, hemolytic anemia, thrombocytopenia]
  • general malaise, loss of appetite, yellowness in skin or in conjunctiva [liver dysfunction, jaundice]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.