くすりのしおり

Internal
Published: 10/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
MANIDIPINE HYDROCHLORIDE Tablets 20mg "YD"
 Active ingredient:
Manidipine hydrochloride
 Dosage form:
light orangish yellow tablet, diameter: approx. 8 mm, thickness: approx. 2.6 mm
 Print on wrapping:
(Face)マニジピン塩酸塩錠20 mg「YD」, 20 mg, マニジピン
(Back)MANIDIPINE HYDROCHLORIDE 20 mg, マニジピン塩酸塩錠20 mg「YD」, 20 mg, 高血圧症治療剤, YD 521

Effects of this medicine

This medicine expands blood vessels by blocking the calcium channel and decreases in blood pressure.
It is usually used to treat hypertension.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant, possibly pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, take 10 to 20 mg of the active ingredient at a time, once a day after breakfast. Start taking 5 mg at a time and the dosage will then be increased as needed. This preparation contains 20 mg of the active ingredient in a tablet. Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause dizziness to decreased blood pressure. Be aware of working at heights or operating dangerous machinery such as driving a car.
  • Do not take grapefruit juice with this medicine, since it may intensify the therapeutic effects of this medicine.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include rash, itching, photosensitivity, gingival hyperplasia, chylous ascites in renal failure patients and gynecomastia. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • dizziness on standing up, dullness, twilight state [transient loss of consciousness due to excessive falloff blood pressure, cerebral infraction]
  • high fever, sore throat, limb subcutaneous bleeding [agranulocytosis, thrombocytopenia]
  • sore throat, high fever, limb subcutaneous bleeding [agranulocytosis, thrombocytopenia]
  • chest discomfort, palpitation, chest pain [ventricular extrasystoles, supraventricular extrasystoles]
  • generalized red rash, skin exfoliation, fever [erythroderma]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from light, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.