くすりのしおり

Self-injection
Published: 12/2018

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
FIRAZYR subcutaneous injection 30mg syringe
 Active ingredient:
Icatibant Acetate
 Dosage form:
injection
 Print on wrapping:

Effects of this medicine

This medicine suppresses vasodilatation and increase in vascular permeability by inhibiting the binding of bradykinin to bradykinin B2 receptor.
It is usually used to treat acute episode of hereditary angioedema.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, subcutaneously inject 1 syringe (30 mg of icatibant), at a time when an acute episode of hereditary angioedema occurs.
    If a sufficient effect is not obtained or symptoms of hereditary angioedema relapse, 1 syringe (30 mg) at a time may be added at an interval of more than 6 hours. The maximum dose frequency is 3 times per 24 hours. Strictly follow the instructions.
  • Inject this medicine into the abdomen.
  • Do not use this medicine if you find the solution has discolored or has particles in it.
  • You may self-inject this medicine (self injection), only if you want to and the doctor has confirmed that you meet certain criteria for the self-injection.
  • Do not reuse the syringes.
  • If an episode of hereditary angioedema occurs in the larynx, inject this medicine, then visit a healthcare facility immediately.
  • If you accidentally inject more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop injecting this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include injection site reaction. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • respiratory distress, rash, swelling around eyes/mouth (lips) [serious hypersensitivity]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Store at 2 to 25 degrees Celsius when storing this medicine at home or in other places.
  • Keep out of reach of children.
  • Put all used syringes into a waste container and discard them as directed by the medical institution.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.