Effects of this medicine
This medicine selectively inhibits thromboxane A2 synthetase, suppresses platelet aggregation and vosoconstriction caused by thromboxane A2. This medicine does not act to cyclooxygenase and prostaglandin synthetase, promotes prostaglandin production to selectively inhibit tromboxane A2 synthetase.
It is usually used to improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid hemorrhage and movement disorder associated with cerebral thrombosis (acute phase).
Before using this medicine, be sure to tell your doctor and pharmacist
- If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
If you have bleeding (hemorrhagic cerebral infarction, epidural bleeding, intracerebral bleeding, primary intraventricular bleeding), cerebral embolism.
- If you are pregnant or breastfeeding.
- If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Dosing schedule (How to take this medicine)
- Your dosing schedule prescribed by your doctor is (( to be written by a healthcare professional))
- To improve cerebrovascular spasms and associated symptoms of cerebral ischemia after surgery for subarachnoid hemorrhage: In general, for adults, this medicine is injected intravenously over a period of 24 hours.
To improve movement disorder associated with cerebral thrombosis (acute phase): In general, for adults, this medicine is injected intravenously over a period of 2 hours, twice a day.
- In general, this medicine is injected for two consecutive weeks in any case.
Possible adverse reactions to this medicine
The most commonly reported adverse reactions include rash, hives, erythema, asthma(-like) attacks, itching, anemia, nausea, diarrhea and fever. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
- headache, subcutaneous bleeding, bloody stool, bloody urine [bleeding]
- decreased blood pressure, respiratory distress, cold feeling [shock, anaphylaxis]
- general malaise, loss of appetite, yellowing of the skin and the white of eyes [liver dysfunction, jaundice]
- nose bleeding, gum bleeding [decreased platelets]
- headache, fever, chills [leucopenia, granulocytopenia]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.