くすりのしおり

Internal
Revised: 4/2019

The information on this sheet is based on approvals granted by the Japanese regulatory authority. Approval details may vary by country. Medicines have adverse reactions (risks) as well as efficacies (benefits). It is important to minimize adverse reactions and maximize efficacy. To obtain a better therapeutic response, patients should understand their medication and cooperate with the treatment.
Brand name :
ARIPIPRAZOLE TABLETS 3mg "OHARA"
 Active ingredient:
Aripiprazole
 Dosage form:
blue tablet, diameter: 6 mm, thickness: 2.5 mm
 Print on wrapping:
(Face)アリピプラゾール 3 mg「オーハラ」, アリピプラゾール, 3 mg
(Back)Aripiprazole 3 mg「OHARA」, アリピプラゾール「オーハラ」, 3 mg

Effects of this medicine

This medicine acts on receptors for dopamine, a neurotransmitter in the brain, to suppress symptoms such as hallucination and delusion and to stabilize unstable mental status. It also improves conditions such as decreased motivation and loss of interest, and symptoms such as uncontrollable excitation and behaviors.
It is usually used to treat schizophrenia.

Before using this medicine, be sure to tell your doctor and pharmacist

  • If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines.
    If you have, or have a past medical or family history of diabetes mellitus.
    If you have liver disorder, cardiovascular disease or hypotension.
    If you have or have a history of convulsive disease such as epilepsy.
    If you have attempted suicide or are considering suicide.
  • If you are pregnant or breastfeeding.
  • If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)

Dosing schedule (How to take this medicine)

  • Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional))
  • In general, for adults, start with taking 2 to 4 tablets (6 to 12 mg of the active ingredient) a day, then take 2 to 8 tablets (6 to 24 mg) a day as a maintenance dose, in 1 to 2 divided doses. The dosage may be adjusted according to age or symptoms. However, the daily dose should not exceed 10 tablets (30 mg). Strictly follow the instructions.
  • If you miss a dose, take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time.
  • If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist.
  • Do not stop taking this medicine unless your doctor instructs you to do so.

Precautions while taking this medicine

  • This medicine may cause drowsiness and decreased attention/concentration/reflex movement. Do not operate dangerous machinery, such as driving a car.
  • Pay attention that alcohol (drinking) may intensify medicinal effects.
  • Uncontrollable behavioral symptoms (impulse control disorders) without regard for adverse social consequences such as a ruined personal life may appear, including repetitive gambling, a pathological increase in sexual desire, repeated excessive unplanned shopping, and binge eating. If any of these symptoms appear, consult with your doctor.

Possible adverse reactions to this medicine

The most commonly reported adverse reactions include insomnia, nervousness, akathisia (unable to keep still), tremor (shivering of limbs), anxiety, weight loss, muscle rigidity, loss of appetite, increased appetite, malaise, somnolence, hypokinesia (expressionless face), salivation (drooling), weight gain, nausea, vomiting, dystonia (muscle tone abnormalities) and constipation. If any of these symptoms occur, consult with your doctor or pharmacist.
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately.
  • dry mouth, excessive intake of water, excessive urination [diabetic ketoacidosis, diabetic coma]
  • being silent without moving, muscle stiffness, acute fever [malignant syndrome]
  • moving the tongue, moving the tongue in and out, constant chewing motion of the mouth [tardive dyskinesia]
  • nausea/vomiting, no output of stool, severe abdominal pain [paralytic ileus]
  • lassitude, muscle pain, reddish brown urine [rhabdomyolysis]
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above.

Storage conditions and other information

  • Keep out of the reach of children. Store away from direct sunlight, heat and moisture.
  • Discard the remainder. Do not store them. Ask your pharmacy or medical institution on how to discard the remainder.
  • [To family members] The patient may experience impulse control disorders such as pathological gambling, a pathological increase in sexual desire, repeated excessive unplanned shopping, and binge eating. Please pay attention to the patient's language and behavior, and if any of these symptoms appear, consult with the patient's doctor.

For healthcare professional use only : Day Month Year

For further information, talk to your doctor or pharmacist.